The International Conference on the Design of Reliable Communication Networks (DRCN) has been held for more than 21 years, addressing resilience topics, such as reliability and availability of communication networks and becoming a meeting point for both industry and academy. DRCN events have always been envisioned as multidisciplinary, putting together scientists from the fields of engineering of survivable equipment and network technologies as well as network management and monitoring, and without forgetting data analytics for fault diagnosis, among others. After all these years, the level of excellence has grown, making DRCN a well-known meeting point, where academia and industry present innovative and challenging results in the mentioned research fields. In 2025, as we hold the 21st edition of DRCN, we are pleased to invite you to contribute and participate in DRCN 2025 on May 12-15 2025, in Ningbo Pan Pacific Hotel, China.